Vargas-Santiago is a Mexican art historian and curator. His specialty is Latin American modern and contemporary art from a transnational and interdisciplinary perspective. He completed a Masters at the National Autonomous University of Mexico (UNAM) and later doctoral studies at the University of Texas at Austin (USA). His doctoral thesis has been supported by the Smithsonian Institute, the Terra Foundation, the Fulbright-García Robles Program, and the National Fund for Culture and Arts, the University of Essex. He has published articles and essays for catalogs in Europe, Latin America and the US. He was cataloguer of the Televisa Foundation Photographic Collection and associate curator of the twentieth century collection at the National Museum of Art (MUNAL). He has co-curated exhibitions such as Looking From the Air: Aerial Photography in Mexico City 1932-1969 (GDF, Mexico, 2007); Matter and Sense: Mexican Art in the Eyes of Octavio Paz (MUNAL Mexico, 2009); Images of the Mexican (Center for the Arts-BOZAR, Belgium, 2010); The Mexican exodus: los héroes En la mira del arte (MUNAL Mexico, 2010). He is currently academic curator at the University Museum of Contemporary Art (MUAC) in Mexico City.